Nomogram for Predicting Individual Survival After Recurrence of Advanced-Stage, High-Grade Ovarian Carcinoma.

ABSTRACT:

Objective

To analyze clinical prognostic factors for survival after recurrence of high-grade, advanced-stage ovarian-peritoneal-tubal carcinoma and to develop a nomogram to predict individual survival after recurrence.

Methods

We retrospectively analyzed patients treated in multicenter Gynecologic Oncology Group protocols for stage III and IV ovarian-peritoneal-tubal carcinoma who underwent primary debulking surgery, received chemotherapy with paclitaxel and a platinum compound, and subsequently developed recurrence. Prognostic factors affecting survival were identified and used to develop a nomogram, which was both internally and externally validated.

Results

There were 4,739 patients included in this analysis, of whom, 84% had stage III and 16% had stage IV ovarian

SUBMITTER: Rose PG 

PROVIDER: S-EPMC6551603 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature