Severity and Variability of Depression Symptoms Predicting Suicide Attempt in High-Risk Individuals.

ABSTRACT: Importance:Predicting suicidal behavior continues to be among the most challenging tasks in psychiatry. Objectives:To examine the trajectories of clinical predictors of suicide attempt (specifically, depression symptoms, hopelessness, impulsivity, aggression, impulsive aggression, and irritability) for their ability to predict suicide attempt and to compute a risk score for suicide attempts. Design, Setting, and Participants:This is a longitudinal study of the offspring of parents (or probands) with mood disorders who were recruited from inpatient units at Western Psychiatric Institute and Clinic (Pittsburgh) and New York State Psychiatric Institute. Participants were recruited from July 15, 1997, to September 6, 2005, and were followed up through January 21, 2014. Probands and offspring (

SUBMITTER: Melhem NM 

PROVIDER: S-EPMC6551844 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature