Time-Frequency Approach Applied to Finding Interaction Regions in Pathogenic Proteins.

ABSTRACT: Protein-protein interactions govern all molecular processes for living organisms, even those involved in pathogen infection. Pathogens such as virus, bacteria, and parasites contain proteins that help the pathogen to attach, penetrate, and settle inside the target cell. Thus, it is necessary to know the regions in pathogenic proteins that interact with host cell receptors. Currently, powerful pathogen databases are available and many pathogenic proteins have been recognized, but many pathogenic proteins have not been characterized. This work developed a program in MATLAB environment based on the time-frequency analysis to recognize important sites in proteins. Our program highlights the highest energy patches in proteins from their time-frequency distribution and matches the corresponding

SUBMITTER: Arenas AF 

PROVIDER: S-EPMC6552352 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature