Optically Responsive, Smart Anti-Bacterial Coatings via the Photofluidization of Azobenzenes.

ABSTRACT: Antibacterial strategies sans antibiotic drugs have recently garnered much interest as a mechanism by which to inhibit biofilm formation and growth on surfaces due to the rise of antibiotic-resistant bacteria. Based on the photofluidization of azobenzenes, we demonstrate for the first time the ability achieve up to a 4 log reduction in bacterial biofilms by opto-mechanically activating the disruption and dispersion of biofilms. This unique strategy with which to enable biofilm removal offers a novel paradigm with which to combat antibiotic resistance.

SUBMITTER: Kehe GM 

PROVIDER: S-EPMC6552654 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature