SUN-341 A Natural History Study for Rare Tumors: An Avenue for Discovering and Understanding Endocrine Cancers

ABSTRACT: Abstract Introduction: Endocrine malignancies, as well as all pediatric cancers, are considered rare tumors, defined as <200,000 affected at any given time in US or <40,000 new cases per year. Rare tumors may present as part of a hereditary cancer syndrome, (e.g multipe endocrine neoplasia type 1) or isolated. These tumors have been traditionally understudied and lack descriptive epidemiology, comprehensive genomic profiles, and phenotypic characterization. In an effort to understand the natural history of these rare cancers, the Pediatric Oncology Branch (POB) of the National Cancer Institute (NCI) has undertaken a rare tumor initiative. Methods: A prospective study has been developed at the NCI to comprehensively and longitudinally evaluate the natural history of patients with rare solid

SUBMITTER: Thomas B 

PROVIDER: S-EPMC6552796 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature