Resurgence of Pertussis Infections in Shandong, China: Space-Time Cluster and Trend Analysis.

ABSTRACT: Although vaccination is effective in preventing infection, pertussis remains endemic worldwide, including China. To lead better targeted prevention strategies, we examined dynamics of spatial and temporal patterns of pertussis transmission in Shandong, China, from 2009 to 2017. We used space-time cluster analysis, logistic regression analysis, and regression tree model to detect the changes in spatial patterns of pertussis infections in Shandong Province, China, between periods (2009-2011, 2012-2014, and 2015-2017). The yearly pertussis incidence rates dramatically increased by 16.8 times from 2009 to 2017. Shifting patterns of peaks of pertussis infections were observed over both time (from June-July to August-September) and space (from Linyi to Jinan), with increasing RR from 4.1 (95% CI

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC6553910 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature