Tenofovir-associated kidney disease in Africans: a systematic review.

ABSTRACT:

Background

Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa. Several previous studies on tenofovir-associated kidney disease in Africa have shown conflicting results. This review summarises what is known about the development of kidney disease in HIV-positive African patients on tenofovir disoproxil fumarate (TDF)-containing ART. We set out to document the occurrence of kidney disease in HIV-positive Africans on TDF-containing ART in population-based studies and to evaluate the renal safety of TDF in Africans.

Methods

We conducted a systemic review using published studies which were identified through a computerized search of original research using the Medline/PubMed

SUBMITTER: Mtisi TJ 

PROVIDER: S-EPMC6554992 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature