Oral and intravenous fosfomycin in complicated urinary tract infections.

ABSTRACT: Urinary tract infections are one of the most common health problems and entail a high consumption of health system resources. Due to the increase in global antibiotic resistances in recent years, it is increasingly common to find uropathogens with multiple resistance mechanisms, including quinolone-resistant bacteria, broad-spectrum β-lactamase producers and carbapenemase producers. In this scenario, the role of fosfomycin has gained considerable importance, given its spectrum of activity against multidrug resistant microorganisms (Gram-positive and Gram-negative), becoming an attractive alternative therapy. Regarding the use of fosfomycin in complicated urinary tract infections, there is increasing clinical experience with patients with infections caused by multidrug resistant bacteria, t

SUBMITTER: Lopez-Montesinos I 

PROVIDER: S-EPMC6555162 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature