Depression is a major risk factor for the development of dementia in people with lower urinary tract symptoms: A nationwide population-based study.

ABSTRACT:

Background/objectives

Studies have shown a strong relationship between depression and dementia. Lower urinary tract symptoms (LUTS) were reported to be independently associated with depression and dementia. However, the relationship between depression and cognitive dysfunction in patients with LUTS is not well characterized.

Method

We conducted a matched cohort study by using a one-million population-based dataset in Taiwan. A total of 15,944 patients with LUTS aged 50 or older were included from 2001 to 2005 and followed up until their death or the end of 2012. During the follow-up period, 1958 cases developed depression subsequently and were defined as the study group. 7832 patients without depression were then identified as control group, matching by age, gender, insuranc

SUBMITTER: Ou MJ 

PROVIDER: S-EPMC6555508 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature