Genetic Basis for Congenital Heart Disease: Revisited: A Scientific Statement From the American Heart Association.

ABSTRACT: This review provides an updated summary of the state of our knowledge of the genetic contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial American Heart Association scientific statement on the genetic basis of congenital heart disease was published, new genomic techniques have become widely available that have dramatically changed our understanding of the causes of congenital heart disease and, clinically, have allowed more accurate definition of the pathogeneses of congenital heart disease in patients of all ages and even prenatally. Information is presented on new molecular testing techniques and their application to congenital heart disease, both isolated and associated with other congenital anomalies or syndromes. Recent advances in the understand

SUBMITTER: Pierpont ME 

PROVIDER: S-EPMC6555769 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature