Abdominal drainage versus no drainage after distal pancreatectomy: study protocol for a randomized controlled trial.

ABSTRACT:

Background

The placement of prophylactic intra-abdominal drains has been common practice in abdominal operations including pancreatic surgery. The PANDRA trial showed that the omission of drains following pancreatic head resection was non-inferior to intra-abdominal drainage in terms of postoperative reinterventions and superior in terms of clinically relevant pancreatic fistula rate and fistula-associated complications. The aim of the present PANDRA II trial is to evaluate the clinical outcome with versus without prophylactic drain placement after distal pancreatectomy.

Methods

The PANDRA II trial is a mono-center, randomized controlled, non-inferiority trial with two parallel study groups. In the control group at least one passive intra-abdominal drain is placed at the pan

SUBMITTER: Kaiser J 

PROVIDER: S-EPMC6555976 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature