Dataset Information

The Epidemiology of Fracture in Patients with Acute Ischemic Stroke in Korea.

ABSTRACT:

Background

Patients who survive an acute phase of stroke are at risk of falls and fractures afterwards. However, it is largely unknown how frequent fractures occur in the Asian stroke population.

Methods

Patients with acute (< 7 days) ischemic stroke who were hospitalized between January 2011 and November 2013 were identified from a prospective multicenter stroke registry in Korea, and were linked to the National Health Insurance Service claim database. The incidences of fractures were investigated during the first 4 years after index stroke. The cumulative incidence functions (CIFs) were estimated by the Gray's test for competing risk data. Fine and Gray model for competing risk data was applied for exploring risk factors of post-stroke fractures.

Results

Among a total of 11,522 patients, 1,616 fracture events were identified: 712 spine fractures, 397 hip fractures and 714 other fractures. The CIFs of any fractures were 2.63% at 6 months, 4.43% at 1 year, 8.09% at 2 years and 13.00% at 4 years. Those of spine/hip fractures were 1.11%/0.61%, 1.88%/1.03%, 3.28%/1.86% and 5.79%/3.15%, respectively. Age by a 10-year increment (hazard ratio [HR], 1.23; 95% confidence interval [CI], 1.17-1.30), women (HR, 1.74; 95% CI, 1.54-1.97), previous fracture (HR, 1.72; 95% CI, 1.54-1.92) and osteoporosis (HR, 1.44; 95% CI, 1.27-1.63) were independent risk factors of post-stroke fracture.

Conclusion

The CIFs of fractures are about 8% at 2 years and 13% at 4 years after acute ischemic stroke in Korea. Older age, women, pre-stroke fracture and osteoporosis raised the risk of post-stroke fractures.

SUBMITTER: Lee KB

PROVIDER: S-EPMC6556443 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

The Epidemiology of Fracture in Patients with Acute Ischemic Stroke in Korea.

Lee Kyung Bok KB Lee Jung Gon JG Kim Beom Joon BJ Kim Jun Yup JY Lee Keon Joo KJ Han Moon Ku MK Park Jong Moo JM Kang Kyusik K Cho Yong Jin YJ Park Hong Kyun HK Hong Keun Sik KS Park Tai Hwan TH Lee Soo Joo SJ Oh Mi Sun MS Yu Kyung Ho KH Lee Byung Chul BC Cha Jae Kwan JK Kim Dae Hyun DH Kim Joon Tae JT Lee Jun J Hong Jeong Ho JH Sohn Sung Il SI Kim Dong Eog DE Choi Jay Chol JC Yeo Min Ju MJ Kim Wook Joo WJ Chae Jae Eun JE Lee Ji Sung JS Lee Juneyoung J Bae Hee Joon HJ

Journal of Korean medical science 20190610 22

<h4>Background</h4>Patients who survive an acute phase of stroke are at risk of falls and fractures afterwards. However, it is largely unknown how frequent fractures occur in the Asian stroke population.<h4>Methods</h4>Patients with acute (< 7 days) ischemic stroke who were hospitalized between January 2011 and November 2013 were identified from a prospective multicenter stroke registry in Korea, and were linked to the National Health Insurance Service claim database. The incidences of fractures ...[more]

PMID: 31172697

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Dataset Information

The Epidemiology of Fracture in Patients with Acute Ischemic Stroke in Korea.

Background

Methods

Results

Conclusion

Publications

The Epidemiology of Fracture in Patients with Acute Ischemic Stroke in Korea.

Similar Datasets

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