Prognostic factors of survival in patients with malignant pleural mesothelioma: an analysis of the National Cancer Database.

ABSTRACT: Malignant pleural mesothelioma (MPM) is a rare disease with a very poor prognosis. Previous studies have indicated that women experience longer survival compared with men. We analyzed 16 267 eligible patients (21.3% females) in the National Cancer Database to evaluate which clinical factors are independently predictive of longer survival. After adjusting for all covariates, survival was significantly better in females compared with males [HRadj: 0.81, 95% confidence interval (CI): 0.77-0.85]. Other factors significantly associated with better survival were younger age at diagnosis, higher income, lower comorbidity score, epithelial histology, earlier stage and receipt of surgical or medical treatment. After propensity matching, survival was significantly better for females compared with ma

SUBMITTER: Van Gerwen M 

PROVIDER: S-EPMC6556702 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature