Challenges in Managing Patients with Hereditary Cancer at Gynecological Services.

ABSTRACT:

Aim

To reveal current problems and challenges faced by our gynecologic services department in managing patients with hereditary cancers.

Methods

We collected clinical data of patients with hereditary cancers, identified via genetic testing (or clinically diagnosed in cases of Cowden syndrome or Peutz-Jeghers syndrome), and treated in our gynecological department from 2012 to 2018.

Results

Fifteen patients had hereditary breast and ovarian cancer (HBOC), 6 had Lynch syndrome, 2 had Cowden syndrome, and 2 had Peutz-Jeghers syndrome. Five patients diagnosed with HBOC were younger than 40 years at diagnosis. Risk-reducing salpingo-oophorectomy (RRSO) was performed on 1 patient with a BRCA1 mutation at age 38 years. Seven patients overall underwent RRSO, and none ha

SUBMITTER: Ueda M 

PROVIDER: S-EPMC6556775 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature