Prognostic significance of the pretreatment prognostic nutritional index in patients with epithelial ovarian cancer.

ABSTRACT:

Objective

We retrospectively investigated the prognostic significance of the pretreatment prognostic nutritional index (PNI) in patients with epithelial ovarian cancer (EOC) according to the clinical stage.

Methods

The baseline characteristics and clinical outcomes of 308 EOC patients were collected and retrospectively reviewed. PNI was defined as 10 × serum albumin (g/L) + 0.005 × lymphocyte count (per mm³) in the peripheral blood. The cut-off value of PNI was defined by time-dependent receiver operating characteristics (ROC) analysis. Univariate or multivariate analysis was conducted to evaluate the association between pretreatment PNI, progression-free survival (PFS), and disease-specific survival (DSS) according to the clinical stage.

Results

The cut-of

SUBMITTER: Komura N 

PROVIDER: S-EPMC6557203 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature