Association between testosterone, semen parameters, and live birth in men with unexplained infertility in an intrauterine insemination population.

ABSTRACT:

Objective

To determine whether men with unexplained infertility and low total T (TT) have abnormal spermatogenesis and lower fecundity.

Design

Secondary analysis of the prospective, randomized, multicenter clinical trial, Assessment of Multiple Intrauterine Gestations from Ovarian Stimulation (AMIGOS).

Setting

Infertility clinics.

Patient(s)

Nine hundred couples with unexplained infertility enrolled in AMIGOS. Semen analysis with an ejaculate of at least 5 million total motile sperm was required for enrollment. For inclusion in this secondary analysis, a fasting TT was required.

Intervention(s)

None.

Main outcome measure(s)

Logistic regression, adjusted for age and body mass index, assessed the association between low TT (defined as <264 ng/dL), s

SUBMITTER: Trussell JC 

PROVIDER: S-EPMC6557574 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature