Stress and Salivary Telomere Length in the Second Half of Life: A Comparison of Life-course Models.

ABSTRACT:

Background

Previous research has explored the relationship between childhood and adulthood stressful life events (SLEs) and adult salivary telomere length (TL), but no research to date has tested different life-course models in which stress in adulthood may fully, partly, or not mediate the relationship between childhood stress and adult TL.

Methods

To fill this gap, we elaborate over previous work by Puterman et al. (2016) and other standard models that do not account for the temporal order of stressors in childhood and adulthood, by using structural equation modeling (SEM) for a sample of 5,754 Health and Retirement Study (HRS) participants to compare the fit of three nested life-course models-social trajectory, early critical period, and cumulative risk.

Results

Re

SUBMITTER: Willis M 

PROVIDER: S-EPMC6557584 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature