The Effect of Upper Airway Surgery on Loop Gain in Obstructive Sleep Apnea.

ABSTRACT:

Study objectives

Controversy exists as to whether elevated loop gain is a cause or consequence of obstructive sleep apnea (OSA). Upper airway surgery is commonly performed in Asian patients with OSA who have failed positive airway pressure therapy and who are thought to have anatomical predisposition to OSA. We hypothesized that high loop gain would decrease following surgical treatment of OSA due to reduced sleep apnea severity.

Methods

Polysomnography was performed preoperatively and postoperatively to assess OSA severity in 30 Chinese participants who underwent upper airway surgery. Loop gain was calculated using a validated clinically-applicable method by fitting a feedback control model to airflow.

Results

Patients were followed up for a median (interquartile ran

SUBMITTER: Li Y 

PROVIDER: S-EPMC6557647 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature