Calibrated Breast Density Measurements.

ABSTRACT: RATIONALE AND OBJECTIVES:Mammographic density is an important risk factor for breast cancer, but translation to the clinic requires assurance that prior work based on mammography is applicable to current technologies. The purpose of this work is to evaluate whether a calibration methodology developed previously produces breast density metrics predictive of breast cancer risk when applied to a case-control study. MATERIALS AND METHODS:A matched case control study (n = 319 pairs) was used to evaluate two calibrated measures of breast density. Two-dimensional mammograms were acquired from six Hologic mammography units: three conventional Selenia two-dimensional full-field digital mammography systems and three Dimensions digital breast tomosynthesis systems. We evaluated the capability of two

SUBMITTER: Fowler EE 

PROVIDER: S-EPMC6557684 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature