Optimizing spatial and seasonal deployment of vaccination campaigns to eliminate wildlife rabies.

ABSTRACT: Understanding how the spatial deployment of interventions affects elimination time horizons and potential for disease re-emergence has broad application to control programmes targeting human, animal and plant pathogens. We previously developed an epidemiological model that captures the main features of rabies spread and the impacts of vaccination based on detailed records of fox rabies in eastern Germany during the implementation of an oral rabies vaccination (ORV) programme. Here, we use simulations from this fitted model to determine the best vaccination strategy, in terms of spatial placement and timing of ORV efforts, for three epidemiological scenarios representative of current situations in Europe. We found that consecutive and comprehensive twice-yearly vaccinations across all regio

SUBMITTER: Baker L 

PROVIDER: S-EPMC6558560 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature