Quantifying the hidden costs of imperfect detection for early detection surveillance.

ABSTRACT: The global spread of pathogens poses an increasing threat to health, ecosystems and agriculture worldwide. As early detection of new incursions is key to effective control, new diagnostic tests that can detect pathogen presence shortly after initial infection hold great potential for detection of infection in individual hosts. However, these tests may be too expensive to be implemented at the sampling intensities required for early detection of a new epidemic at the population level. To evaluate the trade-off between earlier and/or more reliable detection and higher deployment costs, we need to consider the impacts of test performance, test cost and pathogen epidemiology. Regarding test performance, the period before new infections can be first detected and the probability of detecting the

SUBMITTER: Mastin AJ 

PROVIDER: S-EPMC6558562 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature