Influence of Head Tissue Conductivity Uncertainties on EEG Dipole Reconstruction.

ABSTRACT: Reliable EEG source analysis depends on sufficiently detailed and accurate head models. In this study, we investigate how uncertainties inherent to the experimentally determined conductivity values of the different conductive compartments influence the results of EEG source analysis. In a single source scenario, the superficial and focal somatosensory P20/N20 component, we analyze the influence of varying conductivities on dipole reconstructions using a generalized polynomial chaos (gPC) approach. We find that in particular the conductivity uncertainties for skin and skull have a significant influence on the EEG inverse solution, leading to variations in source localization by several centimeters. The conductivity uncertainties for gray and white matter were found to have little influence

SUBMITTER: Vorwerk J 

PROVIDER: S-EPMC6558618 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature