Cardiac hypertrophy is stimulated by altered training intensity and correlates with autophagy modulation in male Wistar rats.

ABSTRACT:

Background

The mechanism for cardiac hypertrophy process that would be a benefit for improvement of cardiovascular endurance needed to be investigated throughly. Specific intensity of training may play a role for homeostasis process in cardiac during training. In the present study, we examine the effect of different intensity of treadmill training on cardiac hypertrophy process and autophagy related gene expression in male wistar rats.

Methods

Three different intensities of treadmill training were conducted on 15 male wistar rats (Low Intensity: 10 m/minute, Moderate Intensity: 20 m/minute, and High Intensity: 30 m/minute) compared to 5 sedentary rats as control. Training duration was 30 min per day, frequency was 5 days per week, during 8 weeks period. Heart weight and hear

SUBMITTER: Gunadi JW 

PROVIDER: S-EPMC6558762 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature