Using kinematic analyses to explore sensorimotor control impairments in children with 22q11.2 deletion syndrome.

ABSTRACT:

Background

The 22q11.2 deletion is associated with psychiatric and behavioural disorders, intellectual disability and multiple physical abnormalities. Recent research also indicates impaired coordination skills may be part of the clinical phenotype. This study aimed to characterise sensorimotor control abilities in children with 22q11.2 deletion syndrome (22q11.2DS) and investigate their relationships with co-occurring IQ impairments and psychopathology.

Methods

Fifty-four children with 22q11.2DS and 24 unaffected sibling controls, comparable in age and gender, underwent kinematic analysis of their hand movements, whilst performing a battery of three visuo-manual coordination tasks that measured their tracking, aiming and steering abilities. Additionally, standardised assess

SUBMITTER: Cunningham AC 

PROVIDER: S-EPMC6558818 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature