Radiotherapy with or without androgen deprivation therapy in intermediate risk prostate cancer?

ABSTRACT:

Objective

Androgen deprivation therapy (ADT) is beneficial for unfavorable intermediate-risk (IR) prostate cancer patients receiving curative radiotherapy (RT). However, for favorable IR patients the latest NCCN guidelines recommends RT alone. We retrospectively studied treatment patterns and outcomes of patients with IR prostate cancer in our institution over the past two decades.

Materials and methods

Three hundred seventy-three IR prostate cancer patients treated with definitive RT between 5/2002-5/2016 were identified in an institutional review board approved database. All patients received conformal RT to the prostate while the vast majority did not receive nodal radiation. ADT was commenced 2 months prior to RT and was continued for 4 months after RT.

Results

Co

SUBMITTER: Amit U 

PROVIDER: S-EPMC6558831 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature