Airport emission particles: exposure characterization and toxicity following intratracheal instillation in mice.

ABSTRACT:

Background

Little is known about the exposure levels and adverse health effects of occupational exposure to airplane emissions. Diesel exhaust particles are classified as carcinogenic to humans and jet engines produce potentially similar soot particles. Here, we evaluated the potential occupational exposure risk by analyzing particles from a non-commercial airfield and from the apron of a commercial airport. Toxicity of the collected particles was evaluated alongside NIST standard reference diesel exhaust particles (NIST2975) in terms of acute phase response, pulmonary inflammation, and genotoxicity after single intratracheal instillation in mice.

Results

Particle exposure levels were up to 1 mg/m³ at the non-commercial airfield. Particulate matter from the non-co

SUBMITTER: Bendtsen KM 

PROVIDER: S-EPMC6558896 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature