Is there a threshold that triggers cortical arousals in obstructive sleep apnea.

ABSTRACT:

Study objectives

To determine whether there is a consistent epiglottic pressure value that predicts respiratory arousal from sleep.

Methods

Thirty-one patients with obstructive sleep apnea underwent overnight polysomnography while instrumented with an epiglottic catheter to measure airway pressures. Nadir epiglottic pressures during respiration events (obstructive apneas/hypopneas) terminated with or without arousals were compared. The events were selected by two methods, (1) 20 events with/without arousals were randomly selected, and (2) Events were sampled in pairs (one terminated with arousal and one without arousal) to minimize the effect of sleep duration/stage on the measurement.

Results

A total of 1,317 respiratory events were analyzed. There was substantial va

SUBMITTER: Li Y 

PROVIDER: S-EPMC6559175 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature