Bone mineral: new insights into its chemical composition.

ABSTRACT: Some compositional and structural features of mature bone mineral particles remain unclear. They have been described as calcium-deficient and hydroxyl-deficient carbonated hydroxyapatite particles in which a fraction of the PO₄^3- lattice sites are occupied by HPO₄^2- ions. The time has come to revise this description since it has now been proven that the surface of mature bone mineral particles is not in the form of hydroxyapatite but rather in the form of hydrated amorphous calcium phosphate. Using a combination of dedicated solid-state nuclear magnetic resonance techniques, the hydrogen-bearing species present in bone mineral and especially the HPO₄^2- ions were closely scrutinized. We show that these HPO₄^2-<

SUBMITTER: Von Euw S 

PROVIDER: S-EPMC6560110 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature