Pre-surgical Language Mapping in Epilepsy: Using fMRI in Chinese-Speaking Patients.

ABSTRACT: Accurate localization of language processing areas is critical in patients undergoing epilepsy surgery. In this study, we aimed to use functional magnetic resonance imaging (fMRI), which is a non-invasive mapping method, to establish a panel of tasks investigating patients' language function. We developed six tasks, including a series of progressive comprehension tasks from words, sentence to text, a verb generation task that can detect subtle left-brain activation, an auditory comprehension task that explored the temporal language-related areas, and a visual object-naming task provided for poorly educated patients. We successfully located the language cortex in 40 patients, and subsequently determined hemispheric dominance for the Chinese language. Our results showed a concordance between

SUBMITTER: Ni B 

PROVIDER: S-EPMC6560162 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature