Designing contrasts for rapid, simultaneous parameter quantification and flow visualization with quantitative transient-state imaging.

ABSTRACT: Magnetic resonance imaging (MRI) has evolved into an outstandingly versatile diagnostic modality, as it has the ability to non-invasively produce detailed information on a tissue's structure and function. Complementary data is normally obtained in separate measurements, either as contrast-weighted images, which are fast and simple to acquire, or as quantitative parametric maps, which offer an absolute quantification of underlying biophysical effects, such as relaxation times or flow. Here, we demonstrate how to acquire and reconstruct data in a transient-state with a dual purpose: 1 - to generate contrast-weighted images that can be adjusted to emphasise clinically relevant image biomarkers; exemplified with signal modulation according to flow to obtain angiography information, and 2 - to

SUBMITTER: Gomez PA 

PROVIDER: S-EPMC6560213 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature