Ontology highlight
ABSTRACT:
SUBMITTER: Jie MM
PROVIDER: S-EPMC6560729 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Jie Meng-Meng MM Chang Xing X Zeng Shuo S Liu Cheng C Liao Guo-Bin GB Wu Ya-Ran YR Liu Chun-Hua CH Hu Chang-Jiang CJ Yang Shi-Ming SM Li Xin-Zhe XZ
Cell communication and signaling : CCS 20190611 1
Human telomerase reverse transcriptase (hTERT) is the core subunit of human telomerase and plays important roles in human cancers. Aberrant expression of hTERT is closely associated with tumorigenesis, cancer cell stemness maintaining, cell proliferation, apoptosis inhibition, senescence evasion and metastasis. The molecular basis of hTERT regulation is highly complicated and consists of various layers. A deep and full-scale comprehension of the regulatory mechanisms of hTERT is pivotal in under ...[more]