Cost-effectiveness of option B+ in prevention of mother-to-child transmission of HIV in Yunnan Province, China.

ABSTRACT:

Background

Although Option B+ may be more costly than Options B, it may provide additional health benefits that are currently unclear in Yunnan province. We created deterministic models to estimate the cost-effectiveness of Option B+.

Methods

Data were used in two deterministic models simulating a cohort of 2000 HIV+ pregnant women. A decision tree model simulated the number of averted infants infections and QALY acquired for infants in the PMTCT period for Options B and B+. The minimum cost was calculated. A Markov decision model simulated the number of maternal life year gained and serodiscordant partner infections averted in the ten years after PMTCT for Option B or B+. ICER per life year gained was calculated. Deterministic sensitivity analyses were conducted.

Results

SUBMITTER: Wang X 

PROVIDER: S-EPMC6560771 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature