Prevalence and profile of adverse drug reactions in high-risk pregnancy: a cohort study.

ABSTRACT:

Background

Commonly used drugs in pregnant women include antihypertensives, hypoglycemic agents, analgesics, antimicrobials, antiemetics and antispasmodics but the use of medicines during pregnancy, especially in high-risk pregnancy, may be associated with high risk of adverse drug reactions (ADR). The objective of this study was to determine the risk of an adverse drug reaction in hospitalized high-risk pregnant women and the factors associated with their occurrence.

Methods

The study received IRB approval and all patients gave written informed consent. Observational cohort study conducted from September 2015 to November 2016 in 1070 pregnant women consecutively admitted to the high risk sector of the University Maternity Januário Cicco in Brazil. ADR were detected through

SUBMITTER: da Silva KDL 

PROVIDER: S-EPMC6560812 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature