Rotavirus antigenemia as a common event among children hospitalised for severe, acute gastroenteritis in Belem, northern Brazil.

ABSTRACT:

Background

Rotavirus antigenemia and RNAemia (the presence of rotavirus RNA in serum) have been commonly identified among paediatric patients with acute gastroenteritis. In this study we examined the association between rotavirus antigenemia and clinical features, and sought to determine the genotypes of rotaviruses detected in paired stool and serum samples.

Methods

Paired stool and serum samples were obtained from children hospitalised for acute gastroenteritis in Belém, Brazil, between June 2012 and June 2015. The 20-point Vesikari scoring system was used to assess the disease severity upon a retrospective medical record review. Stool and serum samples were primarily screened for the presence of rotavirus antigen using a commercial ELISA assay. The rotavirus isolates from

SUBMITTER: Justino MCA 

PROVIDER: S-EPMC6560848 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature