What is the impact of intravitreal injection of conbercept on neovascular glaucoma patients: a prospective, interventional case series study.

ABSTRACT:

Background

The aim of the present study was to evaluate the efficacy and safety of intravitreal conbercept combined with trabeculectomy and panretinal photocoagulation for neovascular glaucoma (NVG).

Methods

Fifty patients (54 eyes) with NVG were included in this prospective study. Fifty-two eyes initially underwent intravitreal conbercept (0.5 mg/0.05 ml) treatment followed by trabeculectomy and panretinal photocoagulation. Preoperative and postoperative best-corrected visual acuity (BCVA), intraocular pressure (IOP), the number of antiglaucoma medications, and surgical complications were recorded. The levels of VEGF-A, TGF-β₁ and PLGF in aqueous humour samples collected during surgery were measured by enzyme-linked immunosorbent assay (ELISA). Light microscopy a

SUBMITTER: Shi L 

PROVIDER: S-EPMC6560891 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature