The contribution of non-malarial febrile illness co-infections to Plasmodium falciparum case counts in health facilities in sub-Saharan Africa.

ABSTRACT:

Background

The disease burden of Plasmodium falciparum malaria illness is generally estimated using one of two distinct approaches: either by transforming P. falciparum infection prevalence estimates into incidence estimates using conversion formulae; or through adjustment of counts of recorded P. falciparum-positive fever cases from clinics. Whilst both ostensibly seek to evaluate P. falciparum disease burden, there is an implicit and problematic difference in the metric being estimated. The first enumerates only symptomatic malaria cases, while the second enumerates all febrile episodes coincident with a P. falciparum infection, regardless of the fever's underlying cause.

Methods

Here, a novel approach was used to triangulate community-based data sources capturing P. falci

SUBMITTER: Dalrymple U 

PROVIDER: S-EPMC6560910 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature