Diagnosis and treatment of Clostridium difficile in adults: a systematic review.

ABSTRACT:

Importance

Since 2000, the incidence and severity of Clostridium difficile infection (CDI) have increased.

Objective

To review current evidence regarding best practices for the diagnosis and treatment of CDI in adults (age ≥ 18 years).

Evidence review

Ovid MEDLINE and Cochrane databases were searched using keywords relevant to the diagnosis and treatment of CDI in adults. Articles published between January 1978 and October 31, 2014, were selected for inclusion based on targeted keyword searches, manual review of bibliographies, and whether the article was a guideline, systematic review, or meta-analysis published within the past 10 years. Of 4682 articles initially identified, 196 were selected for full review. Of these, the most pertinent 116 articles were included.

SUBMITTER: Bagdasarian N 

PROVIDER: S-EPMC6561347 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature