Association between blood pressure and risk of cancer development: a systematic review and meta-analysis of observational studies.

ABSTRACT: With the exception of renal cell carcinoma, studies assessing the association between hypertension and other cancers are inconsistent. We conducted a meta-analysis to assess this evidence. We included observational studies investigating the association between any definition of hypertension or systolic and diastolic blood pressure and risk of any cancer, after searching PubMed until November 2017. We calculated summary relative risks (RR) and 95% confidence intervals (CI) using inverse-variance weighted random effects methods. A total of 148 eligible publications were identified out of 39,891 initially screened citations. Considering only evidence from 85 prospective studies, positive associations were observed between hypertension and kidney, colorectal and breast cancer. Positive associa

SUBMITTER: Seretis A 

PROVIDER: S-EPMC6561976 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature