Profiling of Small Molecular Metabolites in Nostoc flagelliforme during Periodic Desiccation.

ABSTRACT: The mass spectrometry-based metabolomics approach has become a powerful tool for the quantitative analysis of small-molecule metabolites in biological samples. Nostoc flagelliforme, an edible cyanobacterium with herbal value, serves as an unexploited bioresource for small molecules. In natural environments, N. flagelliforme undergoes repeated cycles of rehydration and dehydration, which are interrupted by either long- or short-term dormancy. In this study, we performed an untargeted metabolite profiling of N. flagelliforme samples at three physiological states: Dormant (S1), physiologically fully recovered after rehydration (S2), and physiologically partially inhibited following dehydration (S3). Significant metabolome differences were identified based on the OPLS-DA (orthogonal projection

SUBMITTER: Gao X 

PROVIDER: S-EPMC6562405 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature