Heat Stress-Responsive Transcriptome Analysis in the Liver Tissue of Hu Sheep.

ABSTRACT: Heat stress has a severe effect on animal health and can reduce the productivity and reproductive efficiency; it is therefore necessary to explore the molecular mechanism involved in heat stress response, which is helpful for the cultivation of an animal breed with resistance to heat stress. However, little research about heat stress-responsive molecular analysis has been reported in sheep. Therefore, in this study, RNA sequencing (RNA-Seq) was used to investigate the transcriptome profiling in the liver of Hu sheep with and without heat stress. In total, we detected 520 and 22 differentially expressed mRNAs and lncRNAs, respectively. The differentially expressed mRNAs were mainly associated with metabolic processes, the regulation of biosynthetic processes, and the regulation of glucocort

SUBMITTER: Li Y 

PROVIDER: S-EPMC6562622 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature