Expansion and Functional Divergence of Inositol Polyphosphate 5-Phosphatases in Angiosperms.

ABSTRACT: Inositol polyphosphate 5-phosphatase (5PTase), a key enzyme that hydrolyzes the 5` position of the inositol ring, has essential functions in growth, development, and stress responses in plants, yeasts, and animals. However, the evolutionary history and patterns of 5PTases have not been examined systematically. Here, we report a comprehensive molecular evolutionary analysis of the 5PTase gene family and define four groups. These four groups are different from former classifications, which were based on in vitro substrate specificity. Most orthologous groups appear to be conserved as single or low-copy genes in all lineages in Groups II-IV, whereas 5PTase genes in Group I underwent several duplication events in angiosperm, resulting in multiple gene copies. Whole-genome duplica

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC6562803 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature