Role of Autophagy-Related Gene atg22 in Developmental Process and Virulence of Fusarium oxysporum.

ABSTRACT: Autophagy is a universal catabolic process preserved in eukaryotes from yeast to plants and mammals. The main purpose of autophagy is to degrade cytoplasmic materials within the lysosome/vacuole lumen and generate an internal nutrient pool that is recycled back to the cytosol during nutrient stress. Here, Fusarium oxysporum was utilized as a model organism, and we found that autophagy assumes an imperative job in affecting the morphology, development, improvement and pathogenicity of F. oxysporum. The search of autophagy pathway components from the F. oxysporum genome database recognized putative orthologs of 16 core autophagy-related (ATG) genes of yeast, which additionally incorporate the ubiquitin-like protein atg22. Present study elucidates the unreported role of Foatg22 in formation o

SUBMITTER: Khalid AR 

PROVIDER: S-EPMC6562804 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature