Comparative genome analysis reveals niche-specific genome expansion in Acinetobacter baumannii strains.

ABSTRACT: The nosocomial pathogen Acinetobacter baumannii acquired clinical significance due to the rapid development of its multi-drug resistant (MDR) phenotype. A. baumannii strains have the ability to colonize several ecological niches including soil, water, and animals, including humans. They also survive under extremely harsh environmental conditions thriving on rare and recalcitrant carbon compounds. However, the molecular basis behind such extreme adaptability of A. baumannii is unknown. We have therefore determined the complete genome sequence of A. baumannii DS002, which was isolated from agricultural soils, and compared it with 78 complete genome sequences of A. baumannii strains having complete information on the source of their isolation. Interestingly, the genome of A. baumannii DS002 s

SUBMITTER: Yakkala H 

PROVIDER: S-EPMC6563999 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature