Is there any association between Toxoplasma gondii infection and depression? A systematic review and meta-analysis.

ABSTRACT:

Background

Toxoplasma gondii (T. gondii) is an obligate intracellular opportunistic parasite that is the causative agent of toxoplasmosis. This parasite accounts for mental disorders; however, the relationship between T. gondii infection and depressive disorder is unclear. Regarding this, the present systematic review and meta-analysis was conducted to investigate the scientific evidence regarding the potential association between major depression disorder (MDD) and Toxoplasma infection.

Methods

For the purpose of the study, the articles related to the subject of interest were systematically searched in seven electronic databases. Special attention was given to the studies examining T. gondii seropositivity level in depressed patients and controls.

Results

The search

SUBMITTER: Nayeri Chegeni T 

PROVIDER: S-EPMC6564815 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature