Cognition in adults with Williams syndrome-A 20-year follow-up study.

ABSTRACT:

Background

Williams syndrome (WBS) is a genetic multisystem disorder. The main symptom is borderline (intelligence quotient, IQ 70-79) or abnormally low intelligence (IQ < 70). According to earlier studies young individuals with WBS demonstrate generally a slightly higher verbal IQ (VIQ) compared to performance/nonverbal IQ (PIQ). WBS was recognized as a distinct entity already about 60 years ago, but still cognition in adults with WBS is poorly known.

Methods

We followed 25 adults (age at baseline 19-68, median 38) with genetically confirmed WBS for about 20 years. The study subjects underwent medical and neuropsychological assessments at the baseline and at the end of follow-up.

Results

The mean VIQ remained quite stable from early adulthood up to 40 years of age af

SUBMITTER: Sauna-Aho O 

PROVIDER: S-EPMC6565587 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature