Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy.

ABSTRACT: Hypertrophic cardiomyopathy (HCM) represents one of the most common heritable heart diseases. However, the signalling pathways and regulatory networks underlying the pathogenesis of HCM remain largely unknown. Here, we present a strand-specific RNA-seq dataset for both coding and lncRNA profiling in myocardial tissues from 28 HCM patients and 9 healthy donors. This dataset constitutes a valuable resource for the community to examine the dysregulated coding and lncRNA genes in HCM versus normal conditions.

SUBMITTER: Liu X 

PROVIDER: S-EPMC6565738 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature