Leptin and Ghrelin in Excessive Gestational Weight Gain-Association between Mothers and Offspring.

ABSTRACT: Two-thirds of pregnant women exceed gestational weight gain recommendations. Excessive gestational weight gain (EGWG) appears to be associated with offspring's complications induced by mechanisms that are still unclear. The aim of this study was to investigate whether umbilical cord leptin (UCL) and ghrelin (UCG) concentrations are altered in full-term neonates born to EGWG mothers and whether neonatal anthropometric measurements correlate with UCL and UCG levels and maternal serum ghrelin and leptin as well as urine ghrelin concentrations. The study subjects were divided into two groups, 28 healthy controls and 38 patients with EGWG. Lower UCL and UCG levels were observed in neonates born to healthy mothers but only in male newborns. In the control group UCG concentrations correlated posi

SUBMITTER: Patro-Malysza J 

PROVIDER: S-EPMC6566238 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature