Association of Intake of Whole Grains and Dietary Fiber With Risk of Hepatocellular Carcinoma in US Adults.

ABSTRACT:

Importance

Increased intake of whole grain and dietary fiber has been associated with lower risk of insulin resistance, hyperinsulinemia, and inflammation, which are known predisposing factors for hepatocellular carcinoma (HCC). Therefore, we hypothesized that long-term intake of whole grains and dietary fiber may be associated with lower risk of HCC.

Objective

To assess the associations of whole grain and dietary fiber intake with the risk of HCC.

Design, setting, and participants

Cohort study of the intake of whole grains, their subcomponents (bran and germ), and dietary fiber (cereal, fruit, and vegetable) in 125 455 participants from 2 cohorts from the Nurses' Health Study and the Health Professionals Follow-up Study.

Exposures

Intake of whole grains, their

SUBMITTER: Yang W 

PROVIDER: S-EPMC6567825 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature