Cerebral microbleeds are not associated with postoperative delirium and postoperative cognitive dysfunction in older individuals.

ABSTRACT:

Background

Cerebral microbleeds (CMB) occur in the context of cerebral small vessel disease. Other brain MRI markers of cerebral small vessel disease are associated with the occurrence of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD), but for CMB this is unknown. We aimed to study the association between CMB and the occurrence of POD and POCD in older individuals.

Methods

The current study consists of 65 patients (72±5 years) from the BIOCOG study, which is a prospective, observational study of patients who underwent an elective surgery of at least 60 minutes. Patients in the current study received a preoperative cerebral MRI scan including a 3D susceptibility-weighted imaging sequence to detect CMB. The occurrence of POD was screened for twice

SUBMITTER: Lachmann G 

PROVIDER: S-EPMC6568413 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature