The Role of Oral Antibiotic Preparation in Elective Colorectal Surgery: A Meta-analysis.

ABSTRACT:

Objectives

To compare the impact of the use of oral antibiotics (OAB) with or without mechanical bowel preparation (MBP) on outcome in elective colorectal surgery.

Summary background data

Meta-analyses have demonstrated that MBP does not impact upon postoperative morbidity or mortality, and as such it should not be prescribed routinely. However, recent evidence from large retrospective cohort and database studies has suggested that there may be a role for combined OAB and MBP, or OAB alone in the prevention of surgical site infection (SSI).

Methods

A meta-analysis of randomized controlled trials and cohort studies including adult patients undergoing elective colorectal surgery, receiving OAB with or without MBP was performed. The outcome measures examined were SSI, an

SUBMITTER: Rollins KE 

PROVIDER: S-EPMC6570620 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature